Securities to be offered to employees in employee benefit plans



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As
filed with the Securities and Exchange Commission on February 23, 2023






Registration
No. 333-




















UNITED
STATES








SECURITIES
AND EXCHANGE COMMISSION






Washington,
D.C. 20549














FORM S-8






REGISTRATION
STATEMENT






UNDER






THE
SECURITIES ACT OF 1933
















EQRx, INC.






(Exact
name of registrant as specified in its charter)













































Delaware








86-1691173





(State
or other jurisdiction of




incorporation
or organization)








(I.R.S.
Employer




Identification
No.)














50
Hampshire Street











Cambridge,
Massachusetts








02139




(Address
of Principal Executive Offices)






(Zip
Code)









EQRx, Inc.
2021 Stock Option and Incentive Plan






EQRx, Inc.
2021 Employee Stock Purchase Plan






(

Full
title of the plans

)
















Melanie
Nallicheri






Chief
Executive Officer






EQRx, Inc.






50
Hampshire Street






Cambridge,
Massachusetts 02139






(Name
and address of agent for service)










(617)
315-2255






(Telephone
number, including area code, of agent for service)




























Copies
to:







Dina
Ciarimboli






EQRx, Inc.






50
Hampshire Street






Cambridge,
Massachusetts 02139






Tel:
(617) 315-2255










William
D. Collins, Esq.






Marianne
Sarrazin, Esq.






Goodwin
Procter LLP






100
Northern Avenue






Boston,
Massachusetts 02210






Tel:
(617) 570-1000




















Indicate
by check mark whether the registrant is a large accelerated filer, an accelerated filer, a non-accelerated filer, a smaller reporting
company or an emerging growth company. See the definitions of “large accelerated filer,” “accelerated filer,”
“smaller reporting company,” and “emerging growth company” in Rule 12b-2 of the Exchange Act.




































Large accelerated
filer







x







Accelerated filer






¨



Non-accelerated filer






¨






Smaller reporting company






¨















Emerging growth company






¨








If
an emerging growth company, indicate by check mark if the registrant has elected not to use the extended transition period for complying
with any new or revised financial accounting standards provided pursuant to Section 7(a)(2)(B) of the Securities Act.

¨








































EXPLANATORY
NOTE









EQRx, Inc.
(EQRx) is filing this Registration Statement on Form S-8 for the purpose of registering an additional 24,427,460 shares of its common
stock, par value $0.0001 per share (the Common Stock), under the EQRx, Inc. 2021 Stock Option and Incentive Plan (the 2021 Plan)
and an additional 4,876,326 shares of Common Stock under the EQRx, Inc. 2021 Employee Stock Purchase Plan (the ESPP), pursuant to
the provisions of each plan that provide for annual automatic increases in the number of shares of Common Stock reserved for issuance
under each plan. In each case, the additional shares are of the same class as other securities for which a registration statement relating
to the 2021 Plan and the ESPP has previously been filed and is effective. Accordingly, this registration statement incorporates by reference
the contents of the registration statement on

Form S-8 (File No. 333-262934)

, filed with the Securities and Exchange Commission on February 23, 2022 relating to
the 2021 Plan and the ESPP pursuant to General Instruction E, except with respect to Item 8. Exhibits thereof.









PART II










INFORMATION
REQUIRED IN THE REGISTRATION STATEMENT










Item
8. Exhibits.










EXHIBIT INDEX








































































































































Exhibit






No.









Description












4.1










Second
Amended and Restated Certificate of Incorporation of the registrant (incorporated by reference to Exhibit 3.1 to the Form 8-K
filed December 20, 2021).













4.2










Amended
and Restated Bylaws of the registrant (incorporated by reference to Exhibit 3.2 to the Form 8-K filed December 20,
2021).













4.3










Specimen
Common Stock Certificate (incorporated by reference to Exhibit 4.1 to the Form S-4 (file No. 333-259054) filed October 29,
2021).













5.1*










Opinion
of Goodwin Procter LLP.













23.1*










Consent
of Ernst & Young LLP.
















23.2*










Consent
of Goodwin Procter LLP (included in Exhibit 5.1).













24.1*










Power
of Attorney (included on signature page of this registration statement).













99.1










EQRx, Inc.
2021 Stock Option and Incentive Plan (incorporated by reference to Exhibit 10.8 to the Form 8-K filed December 20,
2021).












99.2








Amendment
No. 1 to EQRx, Inc. 2021 Stock Option and Incentive Plan (incorporated by reference to Exhibit 10.2 to the Form 10-K
filed February 23, 2023).












99.3










Form of
Incentive Stock Option Agreement, Non-Qualified Stock Option Agreement for Non-Employee Directors, Non-Qualified Stock Option Agreement
for Company Employees, Restricted Stock Award Agreement, Restricted Stock Unit Award Agreement for Non-Employee Directors and Restricted
Stock Unit Award Agreement for Company Employees under the EQRX, Inc. 2021 Stock Option and Incentive Plan (incorporated by
reference to Exhibit 10.9 to the Form 8-K filed December 20, 2021).













99.4










EQRx, Inc.
2021 Employee Stock Purchase Plan (incorporated by reference to Exhibit 10.10 to the Form 8-K filed December 20, 2021).













107*










Filing
Fee Table.



























*



Filed herewith.



























SIGNATURES









Pursuant to
the requirements of the Securities Act of 1933, the registrant certifies that it has reasonable grounds to believe that it meets all
of the requirements for filing on Form S-8 and has duly caused this registration statement to be signed on its behalf by the undersigned,
thereunto duly authorized, in the City of Cambridge, Massachusetts, on the 23rd day of February, 2023.




































EQRx, Inc.











By:




/s/ Melanie
Nallicheri





Name:



Melanie
Nallicheri




Title:



Chief Executive
Officer









POWER
OF ATTORNEY AND SIGNATURES









KNOW ALL PERSONS
BY THESE PRESENTS, that each individual whose signature appears below hereby constitutes and appoints each of Melanie Nallicheri and
Jami Rubin as such person’s true and lawful attorney-in-fact and agent with full power of substitution and resubstitution, for
such person in such person’s name, place and stead, in any and all capacities, to sign any and all amendments (including post-effective
amendments) to this registration statement on Form S-8, and to file the same, with all exhibits thereto, and all documents in connection
therewith, with the Commission granting unto each said attorney-in-fact and agent full power and authority to do and perform each and
every act and thing requisite and necessary to be done in and about the premises, as fully to all intents and purposes as such person
might or could do in person, hereby ratifying and confirming all that any said attorney-in-fact and agent, or any substitute or substitutes
of any of them, may lawfully do or cause to be done by virtue hereof.








Pursuant to
the requirements of the Securities Act of 1933, this registration statement has been signed by the following person in the capacities
and on the date indicated below.

















































































































































































































































Signature








Title








Date




/s/
Melanie Nallicheri






President,
Chief Executive Officer and Director






February 23,
2023



Melanie Nallicheri






(Principal Executive Officer)
























/s/
Jami Rubin






Chief Financial Officer






February 23, 2023



Jami Rubin






(Principal Financial and
Accounting Officer)
























/s/
Alexis Borisy






Chairman of the Board






February 23, 2023



Alexis Borisy






























/s/
Amy Abernethy






Director






February 23, 2023



Amy Abernethy






























/s/
Paul Berns






Director






February 23, 2023



Paul Berns






























/s/ Jorge Conde






Director






February 23, 2023



Jorge
Conde






























/s/ Kathryn Giusti






Director






February 23, 2023



Kathryn
Giusti






























/s/ Sandra Horning






Director






February 23, 2023



Sandra
Horning






























/s/ Clive Meanwell






Director






February 23, 2023



Clive
Meanwell






























/s/ Samuel Merksamer






Director






February 23, 2023



Samuel
Merksamer






























/s/ Krishna Yeshwant






Director






February 23, 2023



Krishna
Yeshwant




























The above information was disclosed in a filing to the SEC. To see the filing, click here.

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