Departure of Directors or Certain


On January15, 2019, Chris Stevens, M.D., the Chief Medical Officer of Arsanis, Inc. (the Company), stepped down from the Company, effective immediately.


On January11, 2019, the Compensation Committee of the Companys Board of Directors resolved that, effective upon the termination of Dr.Stevens employment with the Company, the vesting schedule of any outstanding stock options and other equity awards previously granted to Dr.Stevens would be accelerated in full.


Pursuant to the requirements of the Securities Exchange Act of 1934, as amended, the registrant has duly caused this report to be signed on its behalf by the undersigned hereunto duly authorized.

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Date: January16, 2019


/s/ Michael P. Gray

Michael P. Gray

President and Chief Executive Officer

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